One common issue with Mirth (NextGen) Connect is calling 3rd party API via HTTPS, unfortunately, there’s a chance that you’ll get an error like the one below. To resolve this, you need to add the web API’s SSL certificate in your Java KeyStore for Mirth to use.
There are a couple of ways on how to resolve this.
Add the SSL certificates directly in the Java CA keystore on your own using tools like KeyStore Explorer or via terminal.
Using KeyStore Explorer
On my end, I’ll be using KeyStore Explorer which is a free and open-source application that allows you to manage your certificates with a friendly GUI. I previously use Portecle but it hasn’t been updated.